Package index
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DAR_by_LRT()
- Compute p value for DAR test between two cell types
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PIC_counting()
- Count snATAC-seq data matrix with Paired Insertion Counting (PIC)
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count_peaks()
- Count number of paired insertions in each peak
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data_frame_to_GRanges()
- convert peak_set into GRanges object if input is a data.frame
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get_r_by_ct_mat_pq()
- Get region (peak) by cell type matrix and per cell capturing rate
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load_fragments()
- Function for loading fragment files and filter by cell barcodes
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obs_to_insertion_ME()
- Moment estimator for insertion rates from observed values
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obs_to_insertion_MLE_lam()
- Calculate insertion rate from observed PIC counts
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obs_to_insertion_MLE_obj()
- Calculate the optimal loss from observed PIC counts